Lamar Miller - With Miller being inactive, Alfred Blue will see the majority of the work out of the Texans' backfield, but Jonathan Grimes should also get some play. Blue is the suggested start if you need a replacement, though.
A.J. Green - It was thought Green would play in Week 16, and the wide receiver himself also thought he would play, but now it appears he may not return this season at all. Tyler Boyd and Brandon LaFell get a bump, although the Texans have a great pass defense.
Tyler Eifert - The Bengals will be seriously short on Saturday night, as both Green and Eifert will sit. C.J. Uzomah will see plenty of snaps in place of Eifert, who could be shut down for the season.
Who's In: Late Games
Michael Crabtree - There wasn't much doubt about his status. Crabtree is a very attractive option in all formats against a soft Colts defense.
Amari Cooper - Same thing as with Crabtree, as far as his being expected to play. Also, Cooper can be started in all formats in what might be a high-scoring affair versus Indy.
John Brown -Despite being active, you'd be crazy to start Brown in any matchup, let alone in one against an elite defense like the Seahawks.
Who's Out: Late Games
Doug Martin - Whoa. This was unexpected to say the least. From what we know, he's a healthy scratch, unless he injured himself in pregame warmups. In his stead, Jacquizz Rodgers and Charles Sims will both see touches, although figuring out who gets more play is difficult. Rodgers was very successful as a starter earlier in the season, but Sims actually has a future in Tampa Bay. Gun to our head, we're going with Sims over Rodgers, but this is a very risky situation. Alfred Blue is another name to consider with Lamar Miller set to miss Week 16, but again there is risk involved there with Jonathan Grimes likely to be involved. This just sucks all around.
Who’s In: Early Games
Julio Jones - After missing the last two games, Jones is finally active and should be at close to full health. Mohammed Sanu’s value takes a hit, but we still like Taylor Gabriel as he’s performed well even when Jones is in the lineup.
Sammy Watkins - The Bills receiver is set to play on Saturday and will face a Dolphins defense that is decent against the pass.
Stefon Diggs - The Vikings will have their top receiver, which isn’t a surprise considering he was upgraded to full on Friday. Thanks to poor quarterback play, Diggs is a risky matchup against a banged-up Packers secondary.
Cam Newton - Newton was never in doubt, however he was limited during the week. Fire Newton up as a QB1 in a matchup against a Falcons defense that gives up the most fantasy points to quarterbacks.
Brandon Marshall - He'll play against the Patriots, although after posting one catch off of 11 targets last week, we wouldn't trust him as far as we can throw him - and that isn't very far.
Who’s Out: Early Games
Matt Forte - This isn’t much of a surprise, as Forte was doubtful on Friday. In his place, Bilal Powell will see a workhorse role in a tough matchup against the Patriots.
Jordan Reed - This makes things easier for Reed owners, as the star tight end has been playing hurt the last two weeks and totaled just two catches in that span. Vernon Davis is good to go and should be fired up against a Bears defense that has been burned by good tight ends the past six weeks.
Melvin Gordon - The hope is Gordon can suit-up for Week 17 so he can break the 1,000-yard mark, which he’s just three yards away from doing. Kenneth Farrow is a solid start against a Browns defense that is among the league’s worst against the run.
Randall Cobb - Clearly his ankle is still bothering him. He’s been third in the pecking order for the Packers this season, so his absence isn’t much of a boost for Davante Adams or Jordy Nelson.
Adrian Peterson - He has been dealing with knee and groin injuries this week. Obviously, Jerick McKinnon and Matt Asiata get a bump in his place, but neither have been effective this season.